MOA STUDIES By combining the information of a compound with multiple protein targets, prediction algorithms assigns higher scores where the interaction between compounds and targets is more likely.
MOA STUDIES Quantifies the changes in the phosphorylation status of a substrate as a result of treatment with drug candidates.
MOA STUDIES Used to verify and characterize in detail the effect of drug candidates on their targets.
MOA STUDIES Analysis of the alterations in the expression levels of proteins/pathways affected by candidate drugs in treated tissues or cells.
MOA STUDIES Automated sequencing of whole cell or single-cell transcriptome to highlight genes and pathways activated by candidate drugs.
Cell-based or cell-free studies to measure in a competitive or non-competitive fashion target binding of candidate drugs with dose-response and high-throughput settings.